細(xì)胞名稱

人彌漫大B淋巴瘤細(xì)胞TMD8

貨物編碼

BFN60806614

產(chǎn)品規(guī)格

T25培養(yǎng)瓶x1

1.5ml凍存管x2

細(xì)胞數(shù)量

1x10^6

1x10^6

保存溫度

37℃

-198℃

運輸方式

常溫保溫運輸

干冰運輸

安全等級

1

用途限制

僅供科研           1類

培養(yǎng)體系

DMEM高糖+10%FBS+1%雙抗

培養(yǎng)溫度

37℃

二氧化碳濃度

5%

簡介

人彌漫大B淋巴瘤細(xì)胞TMD8取自62歲男性供體。

序列突變

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注釋

Characteristics: Genetic heterogeneous, consists of 3 subclones (PubMed=27566572).

Doubling time: ~30 hours (PubMed=16780947).

Omics: Deep exome analysis.

Omics: Deep RNAseq analysis.

Omics: SNP array analysis.

Omics: Transcriptome analysis.

Misspelling: TDM8; In PubMed=23292937.

Derived from sampling site: Bone marrow.

STR信息

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參考文獻(xiàn)

PubMed=16780947; DOI=10.1016/j.leukres.2006.05.003

Tohda S., Sato T., Kogoshi H., Fu L., Sakano S., Nara N.

Establishment of a novel B-cell lymphoma cell line with suppressed growth by gamma-secretase inhibitors.

Leuk. Res. 30:1385-1390(2006)

PubMed=23292937; DOI=10.1073/pnas.1205299110

Zhang J., Grubor V., Love C.L., Banerjee A., Richards K.L., Mieczkowski P.A., Dunphy C., Choi W., Au W.Y., Srivastava G., Lugar P.L., Rizzieri D.A., Lagoo A.S., Bernal-Mizrachi L., Mann K.P., Flowers C., Naresh K., Evens A., Gordon L.I., Czader M.B., Gill J.I., Hsi E.D., Liu Q., Fan A., Walsh K., Jima D., Smith L.L., Johnson A.J., Byrd J.C., Luftig M.A., Ni T., Zhu J., Chadburn A., Levy S., Dunson D.B., Dave S.S.

Genetic heterogeneity of diffuse large B-cell lymphoma.

Proc. Natl. Acad. Sci. U.S.A. 110:1398-1403(2013)

PubMed=25485619; DOI=10.1038/nbt.3080

Klijn C., Durinck S., Stawiski E.W., Haverty P.M., Jiang Z., Liu H., Degenhardt J., Mayba O., Gnad F., Liu J., Pau G., Reeder J., Cao Y., Mukhyala K., Selvaraj S.K., Yu M., Zynda G.J., Brauer M.J., Wu T.D., Gentleman R.C., Manning G., Yauch R.L., Bourgon R., Stokoe D., Modrusan Z., Neve R.M., de Sauvage F.J., Settleman J., Seshagiri S., Zhang Z.

A comprehensive transcriptional portrait of human cancer cell lines.

Nat. Biotechnol. 33:306-312(2015)

PubMed=27566572; DOI=10.18632/oncotarget.11524

Quentmeier H., Pommerenke C., Ammerpohl O., Geffers R., Hauer V., MacLeod R.A.F., Nagel S., Romani J., Rosati E., Rosen A., Uphoff C.C., Zaborski M., Drexler H.G.

Subclones in B-lymphoma cell lines: isogenic models for the study of gene regulation.

Oncotarget 7:63456-63465(2016)