細胞名稱

人乳腺癌細胞SUM149

貨物編碼

BFN60807665

產品規格

T25培養瓶x1

1.5ml凍存管x2

細胞數量

1x10^6

1x10^6

保存溫度

37℃

-198℃

運輸方式

常溫保溫運輸

干冰運輸

安全等級

1

用途限制

僅供科研        2類

培養體系

90%DMEM+10%FBS+1%雙抗 

培養溫度

37℃

二氧化碳濃度

5%

簡介

人乳腺癌細胞SUM149取自40歲女性

注釋

Group: Triple negative breast cancer (TNBC) cell line.

Transfected with: UniProtKB; P08659; Firefly luciferase.

基因突變

Hemizygous for BRCA1 p.Asn723fs*13 (c.2169delT) (2288delT) (from parent cell line).

Homozygous for CDKN2A deletion (from parent cell line).

Heterozygous for EP300 c.5224+28del3 (from parent cell line).

TP53 p.Met237Ile (c.711G>A) (from parent cell line).

HLA信息

/

STR信息

/

參考文獻

PubMed=20229045; DOI=10.1007/s10585-010-9321-4

Singh B., Cook K.R., Martin C., Huang E.H., Mosalpuria K., Krishnamurthy S., Cristofanilli M., Lucci A.

Evaluation of a CXCR4 antagonist in a xenograft mouse model of inflammatory breast cancer.

Clin. Exp. Metastasis 27:233-240(2010)

PubMed=25279830; DOI=10.1371/journal.pone.0109487

Singh B., Shamsnia A., Raythatha M.R., Milligan R.D., Cady A.M., Madan S., Lucci A.

Highly adaptable triple-negative breast cancer cells as a functional model for testing anticancer agents.

PLoS ONE 9:E109487-E109487(2014)